API

Event: 222

Key Event Title

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Elimination of (high doses), Posterior cardinal vein

Short name

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Elimination of (high doses), Posterior cardinal vein

Key Event Component

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Process Object Action

Key Event Overview


AOPs Including This Key Event

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Stressors

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Level of Biological Organization

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Taxonomic Applicability

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Term Scientific Term Evidence Link
zebrafish Danio rerio Strong NCBI

Life Stages

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Sex Applicability

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How This Key Event Works

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How It Is Measured or Detected

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Methods that have been previously reviewed and approved by a recognized authority should be included in the Overview section above. All other methods, including those well established in the published literature, should be described here. Consider the following criteria when describing each method: 1. Is the assay fit for purpose? 2. Is the assay directly or indirectly (i.e. a surrogate) related to a key event relevant to the final adverse effect in question? 3. Is the assay repeatable? 4. Is the assay reproducible?


Evidence Supporting Taxonomic Applicability

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References

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Chan J, Bayliss PE, Wood JM, Roberts TM. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell. 2002 Apr;1(3):257-67. PubMed PMID: 12086862. (Page 258)