Event: 222
Key Event Title
Elimination of (high doses), Posterior cardinal vein
Short name
Elimination of (high doses), Posterior cardinal veinKey Event Component
| Process | Object | Action |
|---|
Key Event Overview
AOPs Including This Key Event
Stressors
Level of Biological Organization
Taxonomic Applicability
| Term | Scientific Term | Evidence | Link | |
|---|---|---|---|---|
| zebrafish | Danio rerio | Strong | NCBI |
Life Stages
Sex Applicability
How This Key Event Works
How It Is Measured or Detected
Methods that have been previously reviewed and approved by a recognized authority should be included in the Overview section above. All other methods, including those well established in the published literature, should be described here. Consider the following criteria when describing each method: 1. Is the assay fit for purpose? 2. Is the assay directly or indirectly (i.e. a surrogate) related to a key event relevant to the final adverse effect in question? 3. Is the assay repeatable? 4. Is the assay reproducible?
Evidence Supporting Taxonomic Applicability
References
Chan J, Bayliss PE, Wood JM, Roberts TM. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell. 2002 Apr;1(3):257-67. PubMed PMID: 12086862. (Page 258)