API

Event: 458

Key Event Title

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Increased, De Novo FA synthesis

Short name

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Increased, De Novo FA synthesis

Biological Context

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Level of Biological Organization
Cellular

Cell term

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Cell term
hepatocyte


Organ term

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Key Event Components

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Process Object Action
fatty acid biosynthetic process fatty acid increased

Key Event Overview


AOPs Including This Key Event

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AOP Name Role of event in AOP
NR1I3 suppression to steatosis KeyEvent
NRF2/FXR to steatosis KeyEvent

Stressors

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Taxonomic Applicability

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Life Stages

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Sex Applicability

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Key Event Description

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How It Is Measured or Detected

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Domain of Applicability

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References

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