API

Event: 766

Key Event Title

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Inhibition, 4-hydroxyphenyl-pyruvate dioxygenase (HPPD) enzyme

Short name

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Inhibition, 4-hydroxyphenyl-pyruvate dioxygenase (HPPD) enzyme

Biological Context

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Level of Biological Organization
Molecular

Cell term

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Organ term

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Key Event Components

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Process Object Action
4-hydroxyphenylpyruvate dioxygenase activity 4-hydroxyphenylpyruvate dioxygenase (rat) decreased

Key Event Overview


AOPs Including This Key Event

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AOP Name Role of event in AOP
HPPD- corneal papilloma/carcinoma MolecularInitiatingEvent

Stressors

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Taxonomic Applicability

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Life Stages

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Sex Applicability

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Key Event Description

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This key event commonly operates through HPPD inhibitors.


How It Is Measured or Detected

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Domain of Applicability

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Evidence for Perturbation by Stressor


Overview for Molecular Initiating Event

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References

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