API

Event: 786

Key Event Title

?

Increase, Cytotoxicity (hepatocytes)

Short name

?

Increase, Cytotoxicity (hepatocytes)

Biological Context

?

Level of Biological Organization
Cellular

Cell term

?

Cell term
hepatocyte


Organ term

?


Key Event Components

?

Process Object Action
cell death hepatocyte increased

Key Event Overview


AOPs Including This Key Event

?

AOP Name Role of event in AOP
Chronic cytotoxicity- HCC MolecularInitiatingEvent

Stressors

?


Taxonomic Applicability

?


Life Stages

?


Sex Applicability

?


Key Event Description

?


This key event is mediated by Nrf2-related genes.


How It Is Measured or Detected

?



Domain of Applicability

?



Evidence for Perturbation by Stressor


Overview for Molecular Initiating Event

?



References

?