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Key Event Title
Relief, Relief of atopic dermatitis
Key Event Components
Key Event Overview
AOPs Including This Key Event
Key Event Description
Patients with atopic dermatitis who were treated with FK506 ointment for a period of one year enjoyed relief from skin damage (FK506 Ointment Study Group. 1998). Generally, the skin of patients with atopic dermatitis has a higher expression of TLR-1 and a lower expression of TLR-2 than that of healthy subjects, but application of FK506 ointment suppressed expression of TLR-1 and increased expression of TLR-2 (Antiga et al. 2011).