Relationship: 1165
Title
Failure in gamma-glutamyl carboxylation of clotting factors II, VII, IX and X, Under carbo leads to Hemostasis, Depletion from blood of fully functional carboxylated clotting factors
Upstream event
Failure in gamma-glutamyl carboxylation of clotting factors II, VII, IX and X, Under carboDownstream event
Hemostasis, Depletion from blood of fully functional carboxylated clotting factors
Key Event Relationship Overview
AOPs Referencing Relationship
| AOP Name | Directness | Weight of Evidence | Quantitative Understanding |
|---|---|---|---|
| Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage | indirectly leads to | Strong | Strong |