Relationship: 1165
Title
Failure in gamma-glutamyl carboxylation of clotting factors II, VII, IX and X, Under carbo leads to Hemostasis, Depletion from blood of fully functional carboxylated clotting factors
Upstream event
Failure in gamma-glutamyl carboxylation of clotting factors II, VII, IX and X, Under carboDownstream event
Hemostasis, Depletion from blood of fully functional carboxylated clotting factors
Key Event Relationship Overview
AOPs Referencing Relationship
AOP Name | Adjacency | Weight of Evidence | Quantitative Understanding |
---|---|---|---|
Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage | non-adjacent | High | High |