Aopwiki

Relationship: 1857

Title
?

Accumulation, Acetylcholine in synapses leads to Activation, Muscarinic Acetylcholine Receptors

Upstream event
?

Accumulation, Acetylcholine in synapses

Downstream event
?

Activation, Muscarinic Acetylcholine Receptors

Key Event Relationship Overview
?

AOPs Referencing Relationship
?

AOP Name	Adjacency	Weight of Evidence	Quantitative Understanding
Acetylcholinesterase Inhibition Leading to Neurodegeneration	adjacent	High

Taxonomic Applicability
?

Sex Applicability
?

Life Stage Applicability
?

Key Event Relationship Description
?

Evidence Supporting this KER
?

Biological Plausibility
?

Empirical Evidence
?

Uncertainties and Inconsistencies
?

Quantitative Understanding of the Linkage
?

Response-response Relationship
?

Time-scale
?

Known modulating factors
?

Known Feedforward/Feedback loops influencing this KER
?

Domain of Applicability
?

References
?