Relationship: 477
Title
Suppression, Constitutive androstane receptor, NR1l3 leads to demethylation, PPARg promoter
Upstream event
Suppression, Constitutive androstane receptor, NR1l3Downstream event
demethylation, PPARg promoter
Key Event Relationship Overview
AOPs Referencing Relationship
| AOP Name | Directness | Weight of Evidence | Quantitative Understanding |
|---|---|---|---|
| NR1I3 (CAR) suppression leading to hepatic steatosis | directly leads to | Strong | Strong |