Relationship: 661
Title
Overwhelmed, Mitochondrial DNA repair mechanisms leads to Accumulation, Damaged mitochondrial DNA
Upstream event
Overwhelmed, Mitochondrial DNA repair mechanismsDownstream event
Accumulation, Damaged mitochondrial DNA
Key Event Relationship Overview
AOPs Referencing Relationship
| AOP Name | Directness | Weight of Evidence | Quantitative Understanding |
|---|---|---|---|
| Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure | directly leads to |