Relationship: 782
Title
Increase, Regenerative cell proliferation (forestomach epithelial cells) leads to Increase, Hyperplasia (forestomach epithelial cells)
Upstream event
Increase, Regenerative cell proliferation (forestomach epithelial cells)Downstream event
Increase, Hyperplasia (forestomach epithelial cells)
Key Event Relationship Overview
AOPs Referencing Relationship
| AOP Name | Adjacency | Weight of Evidence | Quantitative Understanding |
|---|---|---|---|
| Epithelial cytotoxicity leading to forestomach tumors (in mouse and rat) | adjacent |
Taxonomic Applicability
Sex Applicability
Life Stage Applicability
Key Event Relationship Description
Sustained regenerative cell proliferation directly leads to hyperplasia.