API

Stressor: 129

Title

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Carbendazim

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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User term DTXID Preferred name Casrn jchem_inchi_key indigo_inchi_key
Carbendazim DTXSID4024729 Carbendazim 10605-21-7 TWFZGCMQGLPBSX-UHFFFAOYSA-N TWFZGCMQGLPBSX-UHFFFAOYSA-N

AOP Evidence

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Event Evidence

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Binding, Tubulin

There is no evidence text for this event.



Altered, Chromosome number

A dose of 1000 mg/kg carbendazin administered per os either 4.5 or 6 hr after induction of ovulation significantly increased hyperhaploidy oocytes in Djungarian hamster (Hummler and Hansmann, 1988). The same dose administered at the time of ovulation induction induced a 4-fold increase in hyperhaploidy oocytes over the control values in Syrian Hamsters (JEffay et al 1996).




Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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