AOPs Including This Stressor
|Protein Alkylation leading to Liver Fibrosis||High|
Events Including This Stressor
|User term||DTXID||Preferred name||Casrn||jchem_inchi_key||indigo_inchi_key|
see the chemical list under overall assessment
Characterization of Exposure
George et al. 2001,imethylnitrosamine-induced liver injury in rats: the early deposition of collagen, Toxicology; 2;156(2-3):129-38.
Godoy et al. 1980, Relationship Between Dimethylnitrosamine Metabolism or Activation and Its Ability To Induce Liver Necrosis in Rats, J Natl Cancer Inst, 64(3): 533-538.
Diaz Gomez et al, Further studies on dimethylnitrosamine metabolism, activation and its ability to cause liver injury,1981 Archives of Toxicology;47,3:159-168