API

Stressor: 287

Title

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Propiconazole

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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User term DTXID Preferred name Casrn jchem_inchi_key indigo_inchi_key
Propiconazole DTXSID8024280 Propiconazole 60207-90-1 STJLVHWMYQXCPB-UHFFFAOYNA-N STJLVHWMYQXCPB-UHFFFAOYSA-N

AOP Evidence

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Event Evidence

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CYP7B activity, inhibition

In vitro, propiconazole was shown to bind to the catalytic site of the human recombinant CYP7B and to inhibit its activity (Yantsevich et al., 2014).



Antagonism, Androgen receptor

Using transiently AR-transfected CHO cells, propiconazole showed a LOEC of 12.5 uM and an IC50 of 18 uM (Kjærstad et al, 2010)




Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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