AOPs Including This Stressor
Events Including This Stressor
|CYP7B activity, inhibition|
|Antagonism, Androgen receptor|
|Decreased, Transcription of genes by AR|
|User term||DTXID||Preferred name||Casrn||jchem_inchi_key||indigo_inchi_key|
In vitro, propiconazole was shown to bind to the catalytic site of the human recombinant CYP7B and to inhibit its activity (Yantsevich et al., 2014).
Using transiently AR-transfected CHO cells, propiconazole showed a LOEC of 12.5 uM and an IC50 of 18 uM (Kjærstad et al, 2010)
Using transiently AR-transfected CHO cells, propiconazole showed a LOEC of 12.5 mM and an IC50 of 18 mM (Kjærstad et al. 2010).