API

Stressor: 319

Title

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Acrolein

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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User term DTXID Preferred name Casrn jchem_inchi_key indigo_inchi_key
Acrolein DTXSID5020023 Acrolein 107-02-8 HGINCPLSRVDWNT-UHFFFAOYSA-N HGINCPLSRVDWNT-UHFFFAOYSA-N

AOP Evidence

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Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins during brain development leads to impairment of learning and memory

There is no evidence text for this AOP




Event Evidence

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Binding, Thiol/seleno-proteins involved in protection against oxidative stress

There is no evidence text for this event.



Protein Adduct Formation

LoPachin, R. M. & DeCaprio, A. P. Protein adduct formation as a molecular mechanism in neurotoxicity. Toxicological Sciences 86, 214–225 (2005).




Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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