API

Stressor: 51

Title

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Selected AHR Ligands

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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AOP Evidence

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Event Evidence

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This table is automatically generated and includes the Events with this associated stressor as well as the evidence text from this Event Stressor.



Stressor Info

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Chemical/Category Description

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Chemical properties for a selection of representative AHR ligands are provided in Table 3 in lieu of listing them separately.
Table 2 alt text
Table 3: Chemical and AHR binding properties of selected AHR ligands

This table also provides the EC50, which itself is a measure of potency and one of the determinants of sustained AHR activation. These representative ligands demonstrate the diversity in chemical properties modelling pharmacokinetics and bioavailability as well as sources, including anthropogenic chemicals, dietary constituents, and endogenous substances formed in vivo.



Characterization of Exposure

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References

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