API

Stressor: 60

Title

?

Retinol

Stressor Overview

?


AOPs Including This Stressor

?


Events Including This Stressor

?

Event Name
Alkylation, Protein

Chemical Table

?

User term DTXID Preferred name Casrn jchem_inchi_key indigo_inchi_key
Retinol DTXSID3023556 Retinol 68-26-8 FPIPGXGPPPQFEQ-OVSJKPMPSA-N FPIPGXGPPPQFEQ-OVSJKPMPSA-N

AOP Evidence

?


Protein Alkylation leading to Liver Fibrosis

see the chemical list under overall assessment




Event Evidence

?


Alkylation, Protein

There is no evidence text for this event.




Stressor Info

?



Chemical/Category Description

?



Characterization of Exposure

?



References

?



Takahashi and Breitman 1994 Induction of differentiation and covalent binding to proteins by the synthetic retinoids Ch55 and Am80.Arch Biochem Biophys;314(1):82-9.

Martin et al, 1986,Specific, covalent binding of an azidoretinoid to cellular retinoic acid-binding protein. Biochem Biophys Res Commun.26;135(1):124-30.