AOPs Including This Stressor
Events Including This Stressor
EGFR activation (increased phospho-EGFR (Y1068)) was seen in primary human lobar bronchial epithelial cells incubated with 20 µg/cm2 pine wood smoke particulate matter (WSPM) for 6 h, but not at 2 h (Memon et al., 2020).
In NCI-H292 lung cancer cells stimulated with WSPM2.5 (8 μg/mL), EGFR phosphorylation increased continuously over time, with a significant increase observed at 60 min (Huang et al., 2017).
In the tracehas of rats that were nose-only exposed to smoke from burning Douglas fir wood (25 g) for up to 20 min, Muc5ac gene expression was increased at 24 h post-exposure (Bhattacharyya etal., 2004).