AOPs Including This Stressor
|Oxidative stress [MIE] Leading to Decreased Lung Function [AO]||Low|
Events Including This Stressor
|User term||DTXID||Preferred name||Casrn||jchem_inchi_key||indigo_inchi_key|
|Nitrogen dioxide||DTXSID7020974||Nitrogen dioxide||10102-44-0||JCXJVPUVTGWSNB-UHFFFAOYSA-N||JCXJVPUVTGWSNB-UHFFFAOYSA-N|
Exposure of human bronchial epithelial cells to 100, 400, and 800 ppb NO2 decreased CBF by 2.3±1.7% , 3.0±2.5%, and 6.8±1.7% respectively, which was not significant relative to incubator controls. Exposure of the cells to 2000 ppb NO2 significantly decreased CBF by 14.2±2.5% in comparison with controls (Devalia et al., 1993).