API XML

Aop: 265

AOP Title

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D1 protein blockage leading to photosystem II (PSII)-inhibition associated growth reduction

Short name:

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D1 protein blockage leading to growth reduction

Graphical Representation

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Click to download graphical representation template

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Authors

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You Song1, Li Xie1, Knut Erik Tollefsen1

1 Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, NO-0349 Oslo, Norway

Point of Contact

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You Song   (email point of contact)

Contributors

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  • You Song
  • Knut Erik Tollefsen

Status

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Author status OECD status OECD project SAAOP status
Under development: Not open for comment. Do not cite


This AOP was last modified on May 24, 2018 15:42

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Revision dates for related pages

Page Revision Date/Time
Increase, D1 protein blockage May 24, 2018 15:17
Decrease, Photosystem II activity May 24, 2018 15:17
Decrease, Photosynthesis October 10, 2017 07:51
Decrease, Glycolysis October 10, 2017 07:52
Decrease, Mitochondrial ATP production September 16, 2017 10:14
Decrease, Growth May 24, 2018 15:24
D1 protein blockage leads to PSII activity May 24, 2018 15:25
PSII activity leads to Decrease, Photosynthesis May 24, 2018 15:26
Decrease, Photosynthesis leads to Decrease, Glycolysis October 10, 2017 08:00
Decrease, Glycolysis leads to Decrease, Mitochondrial ATP production May 24, 2018 15:26
Decrease, Mitochondrial ATP production leads to Growth May 24, 2018 15:26
Diuron May 24, 2018 15:29
atrazine November 29, 2016 18:42

Abstract

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Background (optional)

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Summary of the AOP

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Events: Molecular Initiating Events (MIE)

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Key Events (KE)

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Adverse Outcomes (AO)

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Sequence Type Event ID Title Short name
MIE 1516 Increase, D1 protein blockage D1 protein blockage
KE 1517 Decrease, Photosystem II activity PSII activity
KE 1475 Decrease, Photosynthesis Decrease, Photosynthesis
KE 1476 Decrease, Glycolysis Decrease, Glycolysis
KE 40 Decrease, Mitochondrial ATP production Decrease, Mitochondrial ATP production
KE 1521 Decrease, Growth Growth

Relationships Between Two Key Events
(Including MIEs and AOs)

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Title Adjacency Evidence Quantitative Understanding
D1 protein blockage leads to PSII activity adjacent High
PSII activity leads to Decrease, Photosynthesis adjacent High
Decrease, Photosynthesis leads to Decrease, Glycolysis adjacent Moderate
Decrease, Glycolysis leads to Decrease, Mitochondrial ATP production adjacent Moderate
Decrease, Mitochondrial ATP production leads to Growth adjacent Moderate

Network View

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Stressors

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Name Evidence Term
Diuron High
atrazine High

Life Stage Applicability

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Life stage Evidence
Not Otherwise Specified

Taxonomic Applicability

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Term Scientific Term Evidence Link
Lemna minor Lemna minor High NCBI

Sex Applicability

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Overall Assessment of the AOP

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Domain of Applicability

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Essentiality of the Key Events

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Evidence Assessment

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Quantitative Understanding

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Considerations for Potential Applications of the AOP (optional)

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References

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