API

Aop: 86

AOP Title

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Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure

Short name:

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Glucose oxidase - Colony loss

Authors

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Carlie A. LaLone, U.S. Environmental Protection Agency (LaLone.Carlie@epa.gov)

Point of Contact

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Carlie LaLone

Contributors

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  • Carlie LaLone

Status

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Author status OECD status OECD project SAAOP status
Under development: Not open for comment. Do not cite Under Development 1.29 Included in OECD Work Plan


This AOP was last modified on December 03, 2016 16:37

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Revision dates for related pages

Page Revision Date/Time
Decreased, Glucose oxidase enzyme activity September 16, 2017 10:15
Decreased, Hydrogen peroxide production September 16, 2017 10:15
Reduced, Antiseptic incorporated in food December 03, 2016 16:37
Abnormal, Roll change within caste December 03, 2016 16:37
Reduced, Food storage December 03, 2016 16:37
impaired, Larval development December 03, 2016 16:37
Death/Failure, Colony December 03, 2016 16:37
Decreased, Glucose oxidase enzyme activity leads to Decreased, Hydrogen peroxide production December 03, 2016 16:37
Decreased, Hydrogen peroxide production leads to Reduced, Antiseptic incorporated in food December 03, 2016 16:37
Reduced, Antiseptic incorporated in food leads to Abnormal, Roll change within caste December 03, 2016 16:37
Abnormal, Roll change within caste leads to Reduced, Food storage December 03, 2016 16:37
Reduced, Food storage leads to impaired, Larval development December 03, 2016 16:37
impaired, Larval development leads to Death/Failure, Colony December 03, 2016 16:37

Abstract

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Background (optional)

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Summary of the AOP

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Stressors

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Molecular Initiating Event

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Key Events

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Title Short name
Decreased, Glucose oxidase enzyme activity Decreased, Glucose oxidase enzyme activity
Decreased, Hydrogen peroxide production Decreased, Hydrogen peroxide production
Reduced, Antiseptic incorporated in food Reduced, Antiseptic incorporated in food
Abnormal, Roll change within caste Abnormal, Roll change within caste
Reduced, Food storage Reduced, Food storage

Adverse Outcome

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Title Short name
impaired, Larval development impaired, Larval development
Death/Failure, Colony Death/Failure, Colony

Relationships Between Two Key Events (Including MIEs and AOs)

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Network View

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Life Stage Applicability

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Taxonomic Applicability

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Term Scientific Term Evidence Link
Honey bee Honey bee NCBI

Sex Applicability

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Graphical Representation

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Click to download graphical representation template

Overall Assessment of the AOP

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Domain of Applicability

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Essentiality of the Key Events

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Weight of Evidence Summary

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Quantitative Considerations

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Considerations for Potential Applications of the AOP (optional)

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References

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