API XML

Aop: 86

AOP Title

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Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure

Short name:

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Glucose oxidase - Colony loss

Graphical Representation

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Click to download graphical representation template

Authors

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Carlie A. LaLone, U.S. Environmental Protection Agency (LaLone.Carlie@epa.gov)

Point of Contact

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Carlie LaLone   (email point of contact)

Contributors

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  • Carlie LaLone

Status

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Author status OECD status OECD project SAAOP status
Under development: Not open for comment. Do not cite 1.29 Under Development


This AOP was last modified on January 27, 2018 15:34

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Revision dates for related pages

Page Revision Date/Time
Decreased, Glucose oxidase enzyme activity September 16, 2017 10:15
Decreased, Hydrogen peroxide production September 16, 2017 10:15
Reduced, Antiseptic incorporated in food December 03, 2016 16:37
Abnormal, Roll change within caste December 03, 2016 16:37
Reduced, Food storage December 03, 2016 16:37
impaired, Larval development December 03, 2016 16:37
Death/Failure, Colony June 07, 2018 11:15
Decreased, Glucose oxidase enzyme activity leads to Decreased, Hydrogen peroxide production December 03, 2016 16:37
Decreased, Hydrogen peroxide production leads to Reduced, Antiseptic incorporated in food December 03, 2016 16:37
Reduced, Antiseptic incorporated in food leads to Abnormal, Roll change within caste December 03, 2016 16:37
Abnormal, Roll change within caste leads to Reduced, Food storage December 03, 2016 16:37
Reduced, Food storage leads to impaired, Larval development December 03, 2016 16:37
impaired, Larval development leads to Death/Failure, Colony December 03, 2016 16:37

Abstract

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Background (optional)

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Summary of the AOP

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Events: Molecular Initiating Events (MIE)

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Key Events (KE)

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Adverse Outcomes (AO)

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Sequence Type Event ID Title Short name
1 KE 578 Decreased, Glucose oxidase enzyme activity Decreased, Glucose oxidase enzyme activity
2 KE 579 Decreased, Hydrogen peroxide production Decreased, Hydrogen peroxide production
3 KE 580 Reduced, Antiseptic incorporated in food Reduced, Antiseptic incorporated in food
4 KE 564 Abnormal, Roll change within caste Abnormal, Roll change within caste
5 KE 561 Reduced, Food storage Reduced, Food storage
6 AO 566 impaired, Larval development impaired, Larval development
7 AO 563 Death/Failure, Colony Death/Failure, Colony

Relationships Between Two Key Events
(Including MIEs and AOs)

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Title Adjacency Evidence Quantitative Understanding
Decreased, Glucose oxidase enzyme activity leads to Decreased, Hydrogen peroxide production adjacent
Decreased, Hydrogen peroxide production leads to Reduced, Antiseptic incorporated in food adjacent
Reduced, Antiseptic incorporated in food leads to Abnormal, Roll change within caste adjacent
Abnormal, Roll change within caste leads to Reduced, Food storage adjacent
Reduced, Food storage leads to impaired, Larval development adjacent
impaired, Larval development leads to Death/Failure, Colony adjacent

Network View

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Stressors

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Life Stage Applicability

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Taxonomic Applicability

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Term Scientific Term Evidence Link
Honey bee Honey bee NCBI

Sex Applicability

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Overall Assessment of the AOP

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Domain of Applicability

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Essentiality of the Key Events

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Evidence Assessment

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Quantitative Understanding

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Considerations for Potential Applications of the AOP (optional)

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References

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