API

Event: 231

Key Event Title

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Decreased, PPAR-alpha activation

Short name

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Decreased, PPAR-alpha activation

Biological Context

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Level of Biological Organization
Molecular

Cell term

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Cell term
hepatocyte


Organ term

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Key Event Components

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Process Object Action
peroxisome proliferator activated receptor signaling pathway peroxisome proliferator-activated receptor alpha decreased

Key Event Overview


AOPs Including This Key Event

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AOP Name Role of event in AOP
Peroxisomal Fatty Acid Beta-Oxidation Inhibition Leading to Steatosis MolecularInitiatingEvent

Stressors

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Taxonomic Applicability

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Life Stages

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Sex Applicability

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Key Event Description

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How It Is Measured or Detected

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Domain of Applicability

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Evidence for Perturbation by Stressor


Overview for Molecular Initiating Event

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References

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