API

Event: 444

Key Event Title

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Increased, Atrioventricular block and bradycardia

Short name

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Increased, Atrioventricular block and bradycardia

Biological Context

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Level of Biological Organization
Organ


Organ term

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Organ term
heart


Key Event Components

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Process Object Action
atrioventricular block increased
decreased heart rate increased

Key Event Overview


AOPs Including This Key Event

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AOP Name Role of event in AOP
AChE inhibition - acute mortality KeyEvent
sodium channel inhibition 3 KeyEvent

Stressors

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Taxonomic Applicability

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Life Stages

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Sex Applicability

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Key Event Description

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The rhythm of conduction between the atria and ventricles of the heart regulate heart rate. Disruption of heart rhythm can lead to reduced heart rate.


How It Is Measured or Detected

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Atrioventricular block and heart rate can be measured with an electrocardiogram (ECG).


Domain of Applicability

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This key event is only relevant to organisms with a heart.


References

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