API

Relationship: 175

Title

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Activation, LXR leads to Activation, FAS

Upstream event

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Activation, LXR

Downstream event

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Activation, FAS

Key Event Relationship Overview

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AOPs Referencing Relationship

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AOP Name Directness Weight of Evidence Quantitative Understanding
LXR activation leading to hepatic steatosis directly leads to Not Specified
Molecular events lead to nonalcoholic hepatic steatosis (NASH) directly leads to

Taxonomic Applicability

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Sex Applicability

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Life Stage Applicability

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How Does This Key Event Relationship Work

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Weight of Evidence

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Biological Plausibility

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Empirical Support for Linkage

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Uncertainties or Inconsistencies

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Quantitative Understanding of the Linkage

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Evidence Supporting Taxonomic Applicability

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References

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