API

Relationship: 432

Title

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Increased, Atrioventricular block and bradycardia leads to Increased, Mortality

Upstream event

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Increased, Atrioventricular block and bradycardia

Downstream event

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Increased, Mortality

Key Event Relationship Overview

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AOPs Referencing Relationship

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AOP Name Directness Weight of Evidence Quantitative Understanding
Acetylcholinesterase inhibition leading to acute mortality directly leads to Weak Weak

Taxonomic Applicability

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Sex Applicability

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Life Stage Applicability

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How Does This Key Event Relationship Work

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Severe arrhythmias or a heart rate insufficient to supply oxygen to the rest of the body can result in mortality.

Weight of Evidence

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Biological Plausibility

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Empirical Support for Linkage

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Not assembled.

Uncertainties or Inconsistencies

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Quantitative Understanding of the Linkage

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Not evaluated.

Evidence Supporting Taxonomic Applicability

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References

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