API

Relationship: 585

Title

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Inhibition, sodium channel leads to Decreased, Sodium conductance 1

Upstream event

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Inhibition, sodium channel

Downstream event

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Decreased, Sodium conductance 1

Key Event Relationship Overview

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AOPs Referencing Relationship

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AOP Name Directness Weight of Evidence Quantitative Understanding
Sodium channel inhibition leading to reduced survival directly leads to Strong
sodium channel inhibition leading to increased predation directly leads to Strong
Sodium channel inhibition leading to congenital malformations directly leads to Strong

Taxonomic Applicability

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Sex Applicability

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Life Stage Applicability

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How Does This Key Event Relationship Work

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Weight of Evidence

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Biological Plausibility

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Empirical Support for Linkage

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Uncertainties or Inconsistencies

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Quantitative Understanding of the Linkage

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Evidence Supporting Taxonomic Applicability

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References

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