API

Stressor: 262

Title

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Clonixin

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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User term DTXID Preferred name Casrn jchem_inchi_key indigo_inchi_key
Clonixin DTXSID2046121 Clonixin 17737-65-4 CLOMYZFHNHFSIQ-UHFFFAOYSA-N CLOMYZFHNHFSIQ-UHFFFAOYSA-N

AOP Evidence

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Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity

Similar structure and binding affinity as meclofenamic acid.

 

Zhang J, Begum A, Brännström K, Grundström C, Iakovleva I, Olofsson A, Sauer-Eriksson AE, Andersson PL. Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ Sci Technol. 2016 Nov 1;50(21):11984-11993.




Event Evidence

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This table is automatically generated and includes the Events with this associated stressor as well as the evidence text from this Event Stressor.



Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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