API

Stressor: 489

Title

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IL-1 receptor antagonist(IL-1Ra)(Anakinra)

Stressor Overview

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AOPs Including This Stressor

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AOP Name Evidence
Inhibition of IL-1 signaling High

Events Including This Stressor

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Chemical Table

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AOP Evidence

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Inhibition of IL-1 signaling

There is no evidence text for this AOP




Event Evidence

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Blocking of IL-1R

There is no evidence text for this event.



Impaired IL-1 signaling

There is no evidence text for this event.



Inhibition, Nuclear factor kappa B (NF-kB)

There is no evidence text for this event.



Impaired T cell activation

There is no evidence text for this event.



Impaired Ab production

There is no evidence text for this event.



Increase, Increased susceptibility to infection

There is no evidence text for this event.




Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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