API

Stressor: 526

Title

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SARS-CoV

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Binding of viral S-glycoprotein to ACE2 receptor leading to acute respiratory distress associated mortality

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2,https://doi.org/10.1371/journal.ppat.1007236

 Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM (Aug 2005). "A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury". Nature Medicine11 (8): 875–9. doi:10.1038/nm1267PMID 16007097.




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