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Aop: 263
AOP Title
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Chitin synthase inhibition leading to premature molting associated mortality
Short name:
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CHS inhibition leading to mortality
Graphical Representation
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Click to download graphical representation template
Authors
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You Songa
a Section for Environmental Toxicology, Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, NO-0349 Oslo, Norway
Contact: you.song@niva.no
Point of Contact
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You Song
(email point of contact)
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Status
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| Author status |
OECD status |
OECD project |
SAAOP status |
| Under development: Not open for comment. Do not cite |
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This AOP was last modified on June 12, 2018 05:14
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Revision dates for related pages
| Page |
Revision Date/Time |
| Increase, Chitin synthase inhibition |
May 24, 2018 15:57 |
| Decrease, Cuticular chitin synthesis |
May 24, 2018 15:58 |
| Increase, Premature molting |
May 24, 2018 15:58 |
| Increase, Mortality |
December 03, 2016 16:33 |
| Increase, CHS inhibition leads to Decrease, Cuticular chitin synthesis |
May 24, 2018 15:59 |
| Decrease, Cuticular chitin synthesis leads to Increase, Premature molting |
May 24, 2018 15:59 |
| Increase, Premature molting leads to Increase, Mortality |
May 24, 2018 16:00 |
| Nikkomycins |
May 24, 2018 15:54 |
| Polyoxin B |
May 24, 2018 15:54 |
Abstract
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Background (optional)
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Summary of the AOP
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Events: Molecular Initiating Events (MIE)
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Key Events (KE)
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Adverse Outcomes (AO)
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Relationships Between Two Key Events
(Including MIEs and AOs)
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Adjacency |
Evidence |
Quantitative Understanding |
Network View
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Stressors
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Life Stage Applicability
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Taxonomic Applicability
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Sex Applicability
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Overall Assessment of the AOP
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Domain of Applicability
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Essentiality of the Key Events
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Evidence Assessment
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Quantitative Understanding
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Considerations for Potential Applications of the AOP (optional)
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References
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