API
Event: 1670
Key Event Title
Lung cancer
Short name
Lung cancerBiological Context
| Level of Biological Organization |
|---|
| Organ |
Organ term
Key Event Components
| Process | Object | Action |
|---|
Key Event Overview
AOPs Including This Key Event
| AOP Name | Role of event in AOP |
|---|---|
| Frustrated phagocytosis-induced lung cancer | AdverseOutcome |
Stressors
Taxonomic Applicability
| Term | Scientific Term | Evidence | Link | |
|---|---|---|---|---|
| mammals | mammals | NCBI |
Life Stages
| Life stage | Evidence |
|---|---|
| Adult |
Sex Applicability
| Term | Evidence |
|---|---|
| Unspecific |
Key Event Description
Lung cancer is one of the most prevalent cancer in the world. This cancer occur mainly at the level of bronchial cells and affect more rarely at the level of alveoli. Lung cancer affects more men rather than women because of tabacco consumption (trend is reversing). This disease is at the first place on terms of mortality due to the late detection (Cancer League, WHO).
How It Is Measured or Detected
Lung cancer can be measured in human by analysis of the sputum cytology, the chest X-ray and all the techniques usually used in this medical field.
In animal experiments, the OECD guidelines n°451 provide the procedure for the study of carcinogenesis development.
Domain of Applicability
Lung cancer can occur in mammals, male or female, generally in adults