Aopwiki

Event: 462

Key Event Title
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Up Regulation, SCD-1

Short name
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Up Regulation, SCD-1

Key Event Component
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Process	Object	Action
gene expression	acyl-CoA desaturase	increased

Key Event Overview

AOPs Including This Key Event
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AOP Name	Role of event in AOP
NR1I3 (CAR) suppression leading to hepatic steatosis	KeyEvent
NR1I2 (Pregnane X Receptor, PXR) activation leading to hepatic steatosis	KeyEvent
AhR activation leading to hepatic steatosis	KeyEvent

Stressors
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Level of Biological Organization
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Biological Organization
Molecular

Cell term
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Cell term
hepatocyte

Event: 462

Key Event Title
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Short name
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Key Event Component
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Key Event Overview

AOPs Including This Key Event
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Stressors
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Level of Biological Organization
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Cell term
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Organ term
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Taxonomic Applicability
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Life Stages
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Sex Applicability
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How This Key Event Works
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How It Is Measured or Detected
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Evidence Supporting Taxonomic Applicability
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References
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Event: 462

Key Event Title ?

Short name ?

Key Event Component ?

Key Event Overview

AOPs Including This Key Event ?

Stressors ?

Level of Biological Organization ?

Cell term ?

Organ term ?

Taxonomic Applicability ?

Life Stages ?

Sex Applicability ?

How This Key Event Works ?

How It Is Measured or Detected ?

Evidence Supporting Taxonomic Applicability ?

References ?

Key Event Title
?

Short name
?

Key Event Component
?

AOPs Including This Key Event
?

Stressors
?

Level of Biological Organization
?

Cell term
?

Organ term
?

Taxonomic Applicability
?

Life Stages
?

Sex Applicability
?

How This Key Event Works
?

How It Is Measured or Detected
?

Evidence Supporting Taxonomic Applicability
?

References
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