Aopwiki

Event: 663

Key Event Title
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Desensitization, Nicotinic acetylcholine receptor

Short name
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Desensitization, Nicotinic acetylcholine receptor

Key Event Component
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Process	Object	Action
acetylcholine receptor activator activity	Nicotinic acetylcholine receptor	increased
receptor regulator activity		decreased

Key Event Overview

AOPs Including This Key Event
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AOP Name	Role of event in AOP
Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure	KeyEvent
Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste	KeyEvent
Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2	KeyEvent

Stressors
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Level of Biological Organization
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Biological Organization
Molecular

Cell term
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Cell term
neuron

Organ term
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Taxonomic Applicability
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Life Stages
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Sex Applicability
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How This Key Event Works
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How It Is Measured or Detected
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Evidence Supporting Taxonomic Applicability
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References
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