API

Event: 716

Key Event Title

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Increase, Mitogenic cell proliferation (hepatocytes)

Short name

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Increase, Mitogenic cell proliferation (hepatocytes)

Biological Context

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Level of Biological Organization
Cellular

Cell term

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Cell term
hepatocyte


Organ term

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Organ term
liver


Key Event Components

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Process Object Action
cell proliferation mitogenic signaling cell increased
hepatocyte proliferation hepatocyte increased

Key Event Overview


AOPs Including This Key Event

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AOP Name Role of event in AOP
CAR activation- Hepatocellular tumors KeyEvent
AR- HCC KeyEvent
PPARalpha-dependent liver cancer KeyEvent

Stressors

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Taxonomic Applicability

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Life Stages

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Sex Applicability

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Key Event Description

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How It Is Measured or Detected

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Domain of Applicability

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References

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