API

Relationship: 586

Title

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Decreased, Sodium conductance 1 leads to Reduced, swimming speed

Upstream event

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Decreased, Sodium conductance 1

Downstream event

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Reduced, swimming speed

Key Event Relationship Overview

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AOPs Referencing Relationship

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AOP Name Directness Weight of Evidence Quantitative Understanding
Sodium channel inhibition leading to reduced survival indirectly leads to Moderate
sodium channel inhibition leading to increased predation indirectly leads to Moderate
Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival indirectly leads to Weak

Taxonomic Applicability

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Sex Applicability

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Life Stage Applicability

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How Does This Key Event Relationship Work

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Weight of Evidence

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Biological Plausibility

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Empirical Support for Linkage

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Uncertainties or Inconsistencies

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Quantitative Understanding of the Linkage

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Evidence Supporting Taxonomic Applicability

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References

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