API

Stressor: 74

Title

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2,2',4,4'-Tetrahydroxybenzophenone

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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AOP Evidence

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Thyroperoxidase inhibition leading to altered amphibian metamorphosis

There is no evidence text for this AOP



Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity

Zhang J, Begum A, Brännström K, Grundström C, Iakovleva I, Olofsson A, Sauer-Eriksson AE, Andersson PL. Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ Sci Technol. 2016 Nov 1;50(21):11984-11993.




Event Evidence

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Thyroperoxidase, Inhibition

There is no evidence text for this event.




Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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