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Aop: 267
AOP Title
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Uncoupling of oxidative phosphorylation leading to mortality
Short name:
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Uncoupling of OXPHOS leading to mortality
Graphical Representation
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Authors
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You Songa
a Section for Environmental Toxicology, Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, NO-0349 Oslo, Norway
Contact: you.song@niva.no
Point of Contact
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You Song
(email point of contact)
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Status
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| Author status |
OECD status |
OECD project |
SAAOP status |
| Under development: Not open for comment. Do not cite |
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Under Development |
This AOP was last modified on May 01, 2020 13:35
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Revision dates for related pages
| Page |
Revision Date/Time |
| Increase, Uncoupling of oxidative phosphorylation |
June 29, 2017 08:05 |
| Decrease, Mitochondrial ATP production |
September 16, 2017 10:14 |
| Increase, Apoptosis |
April 15, 2017 16:17 |
| Increase, Mortality |
December 03, 2016 16:33 |
| Increase, Uncoupling of OXPHOS leads to Decrease, Mitochondrial ATP production |
June 29, 2017 08:11 |
| Decrease, Mitochondrial ATP production leads to Increase, Apoptosis |
June 12, 2018 04:30 |
| Increase, Apoptosis leads to Increase, Mortality |
June 12, 2018 04:30 |
Abstract
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Summary of the AOP
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Events: Molecular Initiating Events (MIE)
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Key Events (KE)
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Adverse Outcomes (AO)
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(Including MIEs and AOs)
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Overall Assessment of the AOP
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Essentiality of the Key Events
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Considerations for Potential Applications of the AOP (optional)
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References
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