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ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

2096	Occurrence, (Micro)vascular dysfunction Short Name (Micro)vascular dysfunction	4	Tissue	Jan 23, 2023	Jul 31, 2023	385: Viral spike protein interaction with ACE2 leads to microvascular dysfunction, via ACE2 dysregulation
2118	Succinate dehydrogenase, inhibited Short Name SDH, inhibited	3	Molecular	Apr 3, 2023	May 4, 2023	5 AOPs 457: Succinate dehydrogenase inhibition leading to increased insulin resistance through reduction in circulating thyroxine 534: Succinate dehydrogenase (SDH) inhibition leads to oxidative stress 474: Succinate dehydrogenase inactivation leads to cancer by promoting EMT 546: Succinate dehydrogenase inactivation leads to cancer through hypoxic-like mechanisms 588: Inhibition of the mitochondrial complex II of nigro-striatal neurons leads to parkinsonian motor deficits
2120	Superoxide generation, increased Short Name Superoxide generation, increased	1	Cellular	Apr 3, 2023	Apr 17, 2023	457: Succinate dehydrogenase inhibition leading to increased insulin resistance through reduction in circulating thyroxine
2362	Redox cycling of a chemical by mitochondria Short Name Redox cycling	0	Molecular	Sep 5, 2025	Oct 3, 2025	593: Redox cycling of a chemical by mitochondria leads to degeneration of nigrostriatal dopaminergic neurons
2363	Elevated mitochondrial ROS and dysfunction Short Name Mito ROS dysfunction	1	Cellular	Sep 5, 2025	Oct 3, 2025	2 AOPs 593: Redox cycling of a chemical by mitochondria leads to degeneration of nigrostriatal dopaminergic neurons 616: organic UV filter and its Photoproducts reproductive toxicity pathways