Relationship: 2124
Title
Decrease, AR activation leads to Decreased, Transcription of genes by AR
Upstream event
Decrease, AR activationDownstream event
Decreased, Transcription of genes by AR
Key Event Relationship Overview
AOPs Referencing Relationship
| AOP Name | Adjacency | Weight of Evidence | Quantitative Understanding |
|---|---|---|---|
| Decreased testosterone synthesis leading to short anogenital distance (AGD) in male (mammalian) offspring | adjacent | High | Moderate |
| Androgen receptor (AR) antagonism leading to nipple retention (NR) in male (mammalian) offspring | adjacent | Moderate | Moderate |