Stressor: 282

Title

Chemical name selected from established chemical ontologies or, depending on the information available, this could also refer to chemical categories (i.e., groups of chemicals with defined structural features known to trigger the MIE). It can also include non-chemical prototypical stressors such as genetic or environmental factors. More help

Ketoconazole

Stressor Overview

A structured data field that can be used to annotate an AOP with standardized terms identifying prototypical stressors known to trigger the MIE(s)/AOP. More help

AOPs Including This Stressor

This table is automatically generated and lists the AOPs associated with this prototypical stressor. More help

AOP Name	Evidence
Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity	High
Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior
Inhibition of 11β-hydroxylase leading to decresed population trajectory	High

Chemical Table

A list of chemicals associated with a prototypical stressor. More help

User term	DTXID	Preferred name	Casrn	jchem_inchi_key	indigo_inchi_key
Ketoconazole	DTXSID7029879	Ketoconazole	65277-42-1	XMAYWYJOQHXEEK-OZXSUGGESA-N	XMAYWYJOQHXEEK-OZXSUGGESA-N

References

List of the literature that was cited for this prototypical stressor. More help