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ID	Title	Point of Contact	License	MIE	AO	OECD Status	OECD Project

636	Increase in reactive oxygen species (ROS) leading to human amyotrophic lateral sclerosis (ALS)	Shihori Tanabe	All rights reserved	1115: Increase, Reactive oxygen species	2416: human amyotrophic lateral sclerosis (ALS)

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ID	Title	Point of Contact	License	MIE	AO	OECD Status	OECD Project

550	Increased LMNA gene mutation leading to heart failure	Young Jun Kim	BY-SA	2278: Increased LMNA Mutation	1535: Heart failure
558	Phosphodiesterase inhibition leading to heart failure	Young Jun Kim	All rights reserved	2288: Phosphodiesterase inhibition	1535: Heart failure
593	Redox cycling of a chemical by mitochondria leads to degeneration of nigrostriatal dopaminergic neurons	Stefan Schildknecht	BY-SA	2362: Redox cycling of a chemical by mitochondria	896: Parkinsonian motor deficits
613	Peroxisome proliferator-activated receptor alpha activation leading to early life stage mortality via increased reactive oxygen species production	You Song	BY-SA	227: Activation, PPARα	947: Increase, Early Life Stage Mortality
638	Co-exposure to microplastics and cadmium leading to progression from NAFLD to liver tumorigenesis	Wei Mu	BY-SA	3 MIEs 2414: COL3A1 Signaling Pathway 87: Release, Cytokine 1115: Increase, Reactive oxygen species	2 AOs 344: Increase, Liver fibrosis 1395: Liver Cancer