API

Event: 1115

Key Event Title

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Increased, Reactive oxygen species

Short name

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Increased, Reactive oxygen species

Biological Context

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Level of Biological Organization
Cellular

Cell term

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Cell term
eukaryotic cell


Organ term

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Key Event Components

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Process Object Action
reactive oxygen species increased

Key Event Overview


AOPs Including This Key Event

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Stressors

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Taxonomic Applicability

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Life Stages

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Life stage Evidence
All life stages High

Sex Applicability

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Term Evidence
Unspecific High

Key Event Description

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Biological State: increased reactive oxygen species (ROS)

Biological compartment: an entire cell -- may be cytosolic, may also enter organelles.

General role in biology: ROS are a natural product of metabolism. Typically the cell has enough anti-oxidant reducers available to mitigate any potential toxicity from ROS. 


How It Is Measured or Detected

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ROS is typically measured using flourscence or measurements of specific chemical markers.


Domain of Applicability

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ROS is a normal constituent found in all organisms.


References

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