AOP-Wiki

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All Key Events

Showing 751 to 775 of 1907 Key Events

ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

1197	Activation, Fibroblasts Short Name Activation, Fibroblasts	1	Cellular	Nov 29, 2016	Sep 16, 2017	2 AOPs 200: Estrogen receptor activation leading to breast cancer 481: AOPs of amorphous silica nanoparticles: ROS-mediated oxidative stress increased respiratory dysfunction and diseases.
1198	Activation, Macrophages Short Name Activation, Macrophages	1	Cellular	Nov 29, 2016	Sep 16, 2017	3 AOPs 200: Estrogen receptor activation leading to breast cancer 481: AOPs of amorphous silica nanoparticles: ROS-mediated oxidative stress increased respiratory dysfunction and diseases. 462: Activation of reactive oxygen species leading the atherosclerosis
1199	Binding of FK506 to FKBP12, Short Name Binding of FK506 to FKBP12,	0		Nov 29, 2016	Nov 29, 2016	None
1200	Binding of FK506 to FKBP12, Formation Short Name Binding of FK506 to FKBP12, Formation	0		Nov 29, 2016	Nov 29, 2016	None
1201	Binding, Immunophilins Short Name Binding, Immunophilins	1	Molecular	Nov 29, 2016	Oct 17, 2017	None
1202	Suppression, IL-2 and IL-4 production Short Name Suppression, IL-2 and IL-4 production	2	Cellular	Nov 29, 2016	Jun 27, 2021	154: Inhibition of Calcineurin Activity Leading to Impaired T-Cell Dependent Antibody Response
1203	Suppression, Suppression of production of cytotoxic T-cells Short Name	0	Tissue	Nov 29, 2016	Dec 3, 2016	None
1204	Suppression, Suppression of T-cell dependent antibody production Short Name	0	Cellular	Nov 29, 2016	Dec 3, 2016	None
1205	Activation, Juvenile hormone receptor Short Name Activation, Juvenile hormone receptor	1	Molecular	Nov 29, 2016	Sep 16, 2017	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
1206	Induction, Doublesex1 gene Short Name Induction, Doublesex1 gene	1	Molecular	Nov 29, 2016	Sep 16, 2017	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
1207	Induction, Male traits formation in embryos Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1208	Increased, Male offspring Short Name Increased, Male offspring	2	Population	Nov 29, 2016	Dec 3, 2016	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
1209	Induction, Male reproductive tract Short Name Induction, Male reproductive tract	1	Organ	Nov 29, 2016	Sep 16, 2017	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
1210	Alteration, Food-web structures Short Name Alteration, Food-web structures	1	Population	Nov 29, 2016	Dec 3, 2016	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
1211	Altered, food-web structures Short Name Altered, food-web structures	0	Population	Nov 29, 2016	Dec 3, 2016	None
1212	Reduced, Neuronal synaptic inhibition Short Name Reduced, Neuronal synaptic inhibition	0	Cellular	Nov 29, 2016	Dec 3, 2016	None
1213	Increased, Angiogenesis Short Name Increased, Angiogenesis	1	Cellular	Nov 29, 2016	Dec 20, 2022	200: Estrogen receptor activation leading to breast cancer
1214	Altered gene expression specific to CAR activation, Hepatocytes Short Name	1	Cellular	Nov 29, 2016	Dec 19, 2018	107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
1215	TRPA1 activation, TRPA1 Receptor Short Name TRPA1 activation, TRPA1 Receptor	1	Molecular	Nov 29, 2016	Sep 16, 2017	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1216	Influx of Ca2+, Excitation of trigeminal nerves Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1217	Excitation of trigeminal nerves induces Sensory Airway Irritation, Short Name Sensory Airway Irritation	0	Organ	Nov 29, 2016	Sep 24, 2018	None
1218	Opening of calcium channel, Calcium influx Short Name	1	Cellular	Nov 29, 2016	Oct 25, 2017	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1219	Release of Substance P (SP), Substance P increase in circulation Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1220	Trigeminal nerve activation Short Name Excitation, Trigeminal nerve excitation	1	Tissue	Nov 29, 2016	Sep 24, 2018	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1221	Cough, Dyspnea, Sneezing, Acute respiratory effect Short Name	0		Nov 29, 2016	Nov 29, 2016	None