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Showing 1551 to 1575 of 1907 Key Events

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ID Title Event Component Count Biological Organization Created At Last Updated AOPs
2049 Increase, sex ratio (F/M)
0 Individual Aug 28, 2022 Aug 28, 2022 465: Alcohol dehydrogenase leading to reproductive dysfunction
2050 Increase, developmental abnormalities
0 Individual Aug 28, 2022 Aug 28, 2022
2051 Decrease, Tyrosine
0 Molecular Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2052 Decrease, dopa decarboxylase
0 Cellular Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2053 Increase, Defects in tanning of new cuticle
0 Individual Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2054 Increase, impairment of cuticle sclerotization
0 Individual Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2055 Increase, pigmentation
0 Individual Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2056 Increase, delay in oviposition
0 Individual Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2057 Decrease, hatching of egg
0 Individual Aug 28, 2022 Aug 28, 2022 466: Doda decarboxylase leading to mortality
2058 Decrease, 20-hydroxyecdysone
0 Molecular Aug 28, 2022 Aug 28, 2022 467: Knickkopf leading to mortality
2059 Decrease, knickkopf gene
0 Cellular Aug 28, 2022 Aug 28, 2022 467: Knickkopf leading to mortality
2060 Decrease, Chitin laminar organization
0 Tissue Aug 28, 2022 Aug 28, 2022 467: Knickkopf leading to mortality
2061 Decrease, Prevent chitin degradation by chitinases
0 Tissue Aug 28, 2022 Aug 28, 2022 467: Knickkopf leading to mortality
2062 Weak, Procuticle protection
0 Organ Aug 28, 2022 Aug 28, 2022 467: Knickkopf leading to mortality
2063 Decrease, New cuticle secretion
0 Organ Aug 28, 2022 Aug 28, 2022 467: Knickkopf leading to mortality
2064 Increase, Cytosolic calcium
0 Cellular Sep 13, 2022 Sep 13, 2022 265: Uncoupling of oxidative phosphorylation leading to growth inhibition via increased cytosolic calcium
2065 Inhibition, Fatty acid oxidation
0 Cellular Sep 19, 2022 Sep 28, 2022 454: PM2.5-related AOP frameworks on liver diseases
2066 Altered Signaling Pathways
0 Molecular Sep 28, 2022 Feb 13, 2024 550: Increased LMNA gene mutation leading to heart failure
2067 Altered, Nitric Oxide Levels
1 Cellular Sep 28, 2022 Apr 13, 2023 470: Deposition of energy leads to abnormal vascular remodeling
2068 Increase, Endothelial Dysfunction
1 Tissue Sep 28, 2022 Aug 26, 2024
2069 Occurrence, Abnormal Vascular Remodeling
1 Organ Oct 17, 2022 Sep 17, 2024 470: Deposition of energy leads to abnormal vascular remodeling
2070 Increase, Glycolysis
0 Cellular Nov 1, 2022 Nov 1, 2022 267: Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion
2071 Decrease, Glucose pool
0 Cellular Nov 1, 2022 Nov 1, 2022 267: Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion
2072 Increase, Mitochondrial swelling
0 Cellular Nov 1, 2022 Nov 1, 2022 268: Uncoupling of oxidative phosphorylation leading to growth inhibition via mitochondrial swelling
2073 increase oxidation of the di-copper moiety of the hemocyanin active site
0 Molecular Nov 16, 2022 Nov 16, 2022 473: Energy deposition from internalized Ra-226 decay lower oxygen binding capacity of hemocyanin