| 2049 |
Increase, sex ratio (F/M)
Short Name
Increase, sex ratio (F/M)
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
465: Alcohol dehydrogenase leading to reproductive dysfunction
|
| 2050 |
Increase, developmental abnormalities
Short Name
Increase, developmental abnormalities
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
2 AOPs
|
| 2051 |
Decrease, Tyrosine
Short Name
Decrease, Tyrosine
|
0 |
Molecular |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2052 |
Decrease, dopa decarboxylase
Short Name
Decrease, dopa decarboxylase
|
0 |
Cellular |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2053 |
Increase, Defects in tanning of new cuticle
Short Name
Increase, Defects in tanning of new cuticle
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2054 |
Increase, impairment of cuticle sclerotization
Short Name
Increase, impairment of cuticle sclerotization
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2055 |
Increase, pigmentation
Short Name
Increase, pigmentation
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2056 |
Increase, delay in oviposition
Short Name
Increase, delay in oviposition
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2057 |
Decrease, hatching of egg
Short Name
Decrease, hatching of egg
|
0 |
Individual |
Aug 28, 2022 |
Aug 28, 2022 |
466: Doda decarboxylase leading to mortality
|
| 2058 |
Decrease, 20-hydroxyecdysone
Short Name
Decrease, 20-hydroxyecdysone
|
0 |
Molecular |
Aug 28, 2022 |
Aug 28, 2022 |
467: Knickkopf leading to mortality
|
| 2059 |
Decrease, knickkopf gene
Short Name
Decrease, knickkopf gene
|
0 |
Cellular |
Aug 28, 2022 |
Aug 28, 2022 |
467: Knickkopf leading to mortality
|
| 2060 |
Decrease, Chitin laminar organization
Short Name
Decrease, Chitin laminar organization
|
0 |
Tissue |
Aug 28, 2022 |
Aug 28, 2022 |
467: Knickkopf leading to mortality
|
| 2061 |
Decrease, Prevent chitin degradation by chitinases
Short Name
Decrease, Prevent chitin degradation by chitinases
|
0 |
Tissue |
Aug 28, 2022 |
Aug 28, 2022 |
467: Knickkopf leading to mortality
|
| 2062 |
Weak, Procuticle protection
Short Name
Weak, Procuticle protection
|
0 |
Organ |
Aug 28, 2022 |
Aug 28, 2022 |
467: Knickkopf leading to mortality
|
| 2063 |
Decrease, New cuticle secretion
Short Name
Decrease, New cuticle secretion
|
0 |
Organ |
Aug 28, 2022 |
Aug 28, 2022 |
467: Knickkopf leading to mortality
|
| 2064 |
Increase, Cytosolic calcium
Short Name
Increase, Cytosolic Ca
|
0 |
Cellular |
Sep 13, 2022 |
Sep 13, 2022 |
265: Uncoupling of oxidative phosphorylation leading to growth inhibition via increased cytosolic calcium
|
| 2065 |
Inhibition, Fatty acid oxidation
Short Name
Inhibition, Fatty acid oxidation
|
0 |
Cellular |
Sep 19, 2022 |
Sep 28, 2022 |
454: PM2.5-related AOP frameworks on liver diseases
|
| 2066 |
Altered Signaling Pathways
Short Name
Altered Signaling
|
0 |
Molecular |
Sep 28, 2022 |
Feb 13, 2024 |
550: Increased LMNA gene mutation leading to heart failure
|
| 2067 |
Altered, Nitric Oxide Levels
Short Name
Altered, Nitric Oxide Levels
|
1 |
Cellular |
Sep 28, 2022 |
Apr 13, 2023 |
470: Deposition of energy leads to abnormal vascular remodeling
|
| 2068 |
Increase, Endothelial Dysfunction
Short Name
Increase, Endothelial Dysfunction
|
1 |
Tissue |
Sep 28, 2022 |
Aug 26, 2024 |
2 AOPs
|
| 2069 |
Occurrence, Abnormal Vascular Remodeling
Short Name
Occurrence, Abnormal Vascular Remodeling
|
1 |
Organ |
Oct 17, 2022 |
Sep 17, 2024 |
470: Deposition of energy leads to abnormal vascular remodeling
|
| 2070 |
Increase, Glycolysis
Short Name
Increase, Glycolysis
|
0 |
Cellular |
Nov 1, 2022 |
Nov 1, 2022 |
267: Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion
|
| 2071 |
Decrease, Glucose pool
Short Name
Decrease, Glucose pool
|
0 |
Cellular |
Nov 1, 2022 |
Nov 1, 2022 |
267: Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion
|
| 2072 |
Increase, Mitochondrial swelling
Short Name
Increase, Mitochondrial swelling
|
0 |
Cellular |
Nov 1, 2022 |
Nov 1, 2022 |
268: Uncoupling of oxidative phosphorylation leading to growth inhibition via mitochondrial swelling
|
| 2073 |
increase oxidation of the di-copper moiety of the hemocyanin active site
Short Name
methemocyanin formation (decrease overall oxygen binding capacity)
|
0 |
Molecular |
Nov 16, 2022 |
Nov 16, 2022 |
473: Energy deposition from internalized Ra-226 decay lower oxygen binding capacity of hemocyanin
|