Prototypical Stressors

Showing 76 to 100 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

656	Acetaldehyde	Acetaldehyde, CAS-RN: 75-07-0, DTXSID5039224	None
57	Acetaminophen	Acetamide, CAS-RN: 60-35-5, DTXSID7020005 Acetaminophen, CAS-RN: 103-90-2, DTXSID2020006 Acetohexamide, CAS-RN: 968-81-0, DTXSID7020007	260: CYP2E1 activation and formation of protein adducts leading to neurodegeneration
553	acetone	Acetone, CAS-RN: 67-64-1, DTXSID8021482	None
366	Acetyldehyde		None
8	Aceytlsalicylic acid	Aspirin, CAS-RN: 50-78-2, DTXSID5020108	None
319	Acrolein	Acrolein, CAS-RN: 107-02-8, DTXSID5020023	2 AOPs 411: Oxidative stress Leading to Decreased Lung Function 424: Oxidative stress Leading to Decreased Lung Function via CFTR dysfunction
336	Acrylamide	Acrylamide, CAS-RN: 79-06-1, DTXSID5020027	17: Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leads to impairment of learning and memory
501	acrylamio		None
364	Acrylonitrile	Acrylonitrile, CAS-RN: 107-13-1, DTXSID5020029	None
324	Adefovir	Adefovir, CAS-RN: 106941-25-7, DTXSID6046214	256: Inhibition of mitochondrial DNA polymerase gamma leading to kidney toxicity
325	Adefovir dipivoxil	Adefovir dipivoxil, CAS-RN: 142340-99-6, DTXSID5046487	256: Inhibition of mitochondrial DNA polymerase gamma leading to kidney toxicity
61	Aflatoxin B1	Aflatoxin B1, CAS-RN: 1162-65-8, DTXSID9020035	397: Bulky DNA adducts leading to mutations
333	Albumin	Albumin, CAS-RN: 308060-74-4, DTXSID1040409	257: Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity
820	Aldicarb		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
826	Aldrin	Aldrin, CAS-RN: 309-00-2, DTXSID8020040	561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
725	All-trans retinoic acid		615: Suppression of Keap1 cysteine oxidation leading to liver inflammation
731	All-trans retionic acid		436: Inhibition of RALDH2 causes reduced all-trans retinoic acid levels, leading to transposition of the great arteries
697	all-trans-Retinoic acid	all-trans-Retinoic acid, CAS-RN: 302-79-4, DTXSID7021239	None
9	Allyl Alcohol	Allyl alcohol, CAS-RN: 107-18-6, DTXSID8020044	38: Protein Alkylation leading to Liver Fibrosis
120	Alpha-endosulfan		None
227	alpha-tocopheryl succinate		None
116	Alpha,Beta-Thujone		None
763	Altered Gravity		None
720	Aluminum	Aluminum, CAS-RN: 7429-90-5, DTXSID3040273	None
327	Aminoglycosides		257: Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity