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All Key Events

Showing 1151 to 1175 of 1939 Key Events

ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

1235	Non-neuronal production of IL-8/CXCL1, Epithelial irritation Short Name	3	Tissue	Nov 29, 2016	Dec 3, 2016	None
1234	Production of nerve growth factor , Epithelial irritation Short Name	2	Tissue	Nov 29, 2016	Dec 3, 2016	None
1233	Production, Nerve growth factor Short Name Production, Nerve growth factor	0		Nov 29, 2016	Nov 29, 2016	None
1232	Production of nerve growth factor , Short Name Production of nerve growth factor ,	0		Nov 29, 2016	Nov 29, 2016	None
1231	Oxidization of biomolecules, Lipid bilayer and cellular proteins Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1230	TRPV1 activation, TRPV1 Short Name TRPV1 activation, TRPV1	1	Molecular	Nov 29, 2016	Dec 3, 2016	None
1229	TRPA1 activation, Chemical covalent binding to sulfhydyl group on TRPA1 receptor protein/ HEK293 fibroblast cells Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1228	TRPA1 activation, Classic receptor binding / HEK 293 cells (fibroclast), cho cells (ovary), noncovalently linkked) Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1227	TRPA1 activation, Chemical covalent binding to sulfhydyl group on TRPA1 receptor protein/NEK293 fibroblast cells Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1226	Increased Respiratory irritability and Chronic Cough, Short Name Respiratory irritability	2	Organ	Nov 29, 2016	Sep 24, 2018	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1225	Immune system inflammation Short Name Leukocyte infiltration	2	Tissue	Nov 29, 2016	Sep 16, 2017	None
1224	Non-neuronal production of TNF, Epithelial irritation Short Name	2	Individual	Nov 29, 2016	Dec 3, 2016	None
1223	Trigeminal and/or vagal nerve excitation causes Airway Hyper-responsiveness,Cough, Dyspnea Short Name	4	Tissue	Nov 29, 2016	Sep 24, 2018	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1222	SP (Substance P) release, Local increase of SP Short Name	1	Cellular	Nov 29, 2016	Sep 16, 2017	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1221	Cough, Dyspnea, Sneezing, Acute respiratory effect Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1220	Trigeminal nerve activation Short Name Excitation, Trigeminal nerve excitation	1	Tissue	Nov 29, 2016	Sep 24, 2018	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1219	Release of Substance P (SP), Substance P increase in circulation Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1218	Opening of calcium channel, Calcium influx Short Name	1	Cellular	Nov 29, 2016	Oct 25, 2017	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1217	Excitation of trigeminal nerves induces Sensory Airway Irritation, Short Name Sensory Airway Irritation	0	Organ	Nov 29, 2016	Sep 24, 2018	None
1216	Influx of Ca2+, Excitation of trigeminal nerves Short Name	0		Nov 29, 2016	Nov 29, 2016	None
1215	TRPA1 activation, TRPA1 Receptor Short Name TRPA1 activation, TRPA1 Receptor	1	Molecular	Nov 29, 2016	Sep 16, 2017	196: Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation
1214	Altered gene expression specific to CAR activation, Hepatocytes Short Name	1	Cellular	Nov 29, 2016	Dec 19, 2018	107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
1213	Increased, Angiogenesis Short Name Increased, Angiogenesis	1	Cellular	Nov 29, 2016	Dec 20, 2022	200: Estrogen receptor activation leading to breast cancer
1212	Reduced, Neuronal synaptic inhibition Short Name Reduced, Neuronal synaptic inhibition	0	Cellular	Nov 29, 2016	Dec 3, 2016	None
1211	Altered, food-web structures Short Name Altered, food-web structures	0	Population	Nov 29, 2016	Dec 3, 2016	None