Prototypical Stressors

Showing 326 to 350 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

345	Endosulfan	Endosulfan, CAS-RN: 115-29-7, DTXSID1020560	2 AOPs 10: Binding to the picrotoxin site of ionotropic GABA receptors leading to epileptic seizures in adult brain 561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
350	Enflurane	Enflurane, CAS-RN: 13838-16-9, DTXSID1020562	260: CYP2E1 activation and formation of protein adducts leading to neurodegeneration
807	Enoximone		558: Phosphodiesterase inhibition leading to heart failure
423	Entacapone	Entacapone, CAS-RN: 130929-57-6, DTXSID5046439	None
407	Epidermal growth factor	Epidermal growth factor, CAS-RN: 62229-50-9, DTXSID5040469	None
615	epigallocathechin gallate		None
796	Epinephrine		554: β-adrenergic receptor agonists leading to arrhythmias.
408	Epothilone A	Epothilone A, CAS-RN: 152044-53-6, DTXSID10332288	None
409	Epothilone B	Epothilone B, CAS-RN: 152044-54-7, DTXSID4046862	None
559	Epoxiconazole	Epoxiconazole, CAS-RN: 133855-98-8, DTXSID1040372	None
700	Escitalopram	Escitalopram, CAS-RN: 128196-01-0, DTXSID8048440	None
105	Esfenvalerate	Esfenvalerate, CAS-RN: 66230-04-4, DTXSID4032667	None
452	Estrogen		None
360	Ethanol	Ethanol, CAS-RN: 64-17-5, DTXSID9020584	2 AOPs 260: CYP2E1 activation and formation of protein adducts leading to neurodegeneration 436: Inhibition of RALDH2 causes reduced all-trans retinoic acid levels, leading to transposition of the great arteries
154	Ethyl acetate	Ethyl acetate, CAS-RN: 141-78-6, DTXSID1022001	None
737	Ethyl alcohol		443: DNA damage and mutations leading to Metastatic Breast Cancer
22	Ethyl methanesulfonate	Ethyl methanesulfonate, CAS-RN: 62-50-0, DTXSID6025309	550: Increased LMNA gene mutation leading to heart failure
23	Ethyl nitrosourea	1-Ethyl-1-nitrosourea, CAS-RN: 759-73-9, DTXSID8020593	None
651	Ethyl Parathion		2 AOPs 405: Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function 450: Inhibition of AChE and activation of CYP2E1 leading to sensory axonal peripheral neuropathy and mortality
24	Ethyl-N'-nitro-N-nitrosoguanidine	N′-Ethyl-N-nitro-N-nitrosoguanidine, CAS-RN: 63885-23-4, DTXSID3020592	None
25	Ethylene thiourea	Ethylene thiourea, CAS-RN: 96-45-7, DTXSID5020601	271: Inhibition of thyroid peroxidase leading to impaired fertility in fish
56	Ethylenethiourea	Ethylene thiourea, CAS-RN: 96-45-7, DTXSID5020601	None
576	Etomidate	Etomidate, CAS-RN: 33125-97-2, DTXSID5023033	349: Inhibition of 11β-hydroxylase leading to decresed population trajectory
223	Etoposide	Etoposide, CAS-RN: 33419-42-0, DTXSID5023035	202: Inhibitor binding to topoisomerase II leading to infant leukaemia
281	etoposide quinone		202: Inhibitor binding to topoisomerase II leading to infant leukaemia