Prototypical Stressors

Showing 526 to 550 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

669	Mycotoxin	Mycotoxin, CAS-RN: NOCAS, DTXSID0040884	None
572	N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide		348: Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory
80	N-methyl Carbamates		405: Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function
833	N-Methyl-D-aspartic acid	N-Methyl-D-aspartic acid, CAS-RN: 6384-92-5, DTXSID8041082	475: Binding of chemicals to ionotropic glutamate receptors leads to impairment of learning and memory via loss of drebrin from dendritic spines of neurons
268	n/a		None
589	Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide		None
588	Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide Pimozide		None
315	Nabam-sodium	Nabam-sodium, CAS-RN: 142-59-6, DTXSID5020603	242: Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity
206	Nafenopin	Nafenopin, CAS-RN: 3771-19-5, DTXSID8020911	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
634	nanomaterials		2 AOPs 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
224	nanoparticles		3 AOPs 144: Endocytic lysosomal uptake leading to liver fibrosis 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
733	Nanoparticles and micrometer		None
717	Nanoparticles and Micrometer Particles		None
860	Naphthalene	Naphthalene, CAS-RN: 91-20-3, DTXSID8020913	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
230	naphtharazine		None
41	Naproxen	Naproxen, CAS-RN: 22204-53-1, DTXSID4040686	None
421	Nefazodone	Nefazodone, CAS-RN: 83366-66-9, DTXSID2023357	None
398	Nefazodone, Amiodarone, Benzbromarone, Metformin, Entacapone		None
394	Nefazodone, Amiodarone, Flutamide, Benzbromarone, Metformin, Tolcapone, Entacapone, Diclofenac		None
400	Nefazodone, Amiodarone, Metformin, Diclofenac		None
814	Neostigmine		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
301	NFE2/Nrf2 repression		232: NFE2/Nrf2 repression to steatosis
759	NH-375		485: Thyroid hormone antagonism leading to impaired oligodendrocyte maturation during development and subsequent decreased cognition
722	Nickel	Nickel, CAS-RN: 7440-02-0, DTXSID2020925	None
743	Niclosamide ethanolamine		263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation