| 2241 |
Ferroptosis related pathways activation
Short Name
Ferroptosis related pathways activation
|
0 |
Cellular |
Jul 9, 2024 |
Jul 9, 2024 |
538: Adverse outcome pathway of PFAS-induced vascular disrupting effects via activating oxidative stress related pathways
|
| 2240 |
The NO synthase pathway activation
Short Name
The NO synthase pathway activation
|
0 |
Cellular |
Jul 9, 2024 |
Jul 9, 2024 |
538: Adverse outcome pathway of PFAS-induced vascular disrupting effects via activating oxidative stress related pathways
|
| 2239 |
Increased, Cardiac stress
Short Name
Increased, Cardiac stress
|
1 |
Organ |
Jul 8, 2024 |
Dec 3, 2024 |
539: Decreased Sodium/Potassium ATPase activity leads to Heart failure
|
| 2238 |
Increased, Blood viscosity
Short Name
Increased, Blood viscosity
|
1 |
Tissue |
Jul 8, 2024 |
Dec 3, 2024 |
539: Decreased Sodium/Potassium ATPase activity leads to Heart failure
|
| 2237 |
Decreased, Plasma sodium concentrations
Short Name
Decreased, Plasma sodium concentrations
|
1 |
Tissue |
Jul 8, 2024 |
Dec 3, 2024 |
539: Decreased Sodium/Potassium ATPase activity leads to Heart failure
|
| 2236 |
Decreased, Sodium uptake in gills
Short Name
Decreased, sodium uptake in gills
|
1 |
Cellular |
Jul 8, 2024 |
Dec 3, 2024 |
539: Decreased Sodium/Potassium ATPase activity leads to Heart failure
|
| 2235 |
Increased incidence and mortality of liver diseases among children
Short Name
Increased incidence and mortality of liver diseases among children
|
0 |
Population |
Jun 26, 2024 |
Jun 26, 2024 |
None
|
| 2234 |
Malignant transformation of cells
Short Name
Malignant transformation of cells
|
0 |
Cellular |
Jun 26, 2024 |
Jun 26, 2024 |
None
|
| 2233 |
Decreased, ERαβ heterodimers
Short Name
Decreased, ERαβ heterodimers
|
0 |
Molecular |
Jun 19, 2024 |
Jun 19, 2024 |
535: Binding and activation of GPER leading to learning and memory impairments
|
| 2232 |
Antagonism, Retinoic acid receptors
Short Name
RAR antagonism
|
0 |
Molecular |
Jun 6, 2024 |
Jun 6, 2024 |
533: Retinoic acid receptor antagonism during neurodevelopment leading to impaired learning and memory
|
| 2231 |
Locomotor function. Impaired
Short Name
Impaired locomotor function
|
0 |
Population |
Jun 6, 2024 |
Jun 6, 2024 |
2 AOPs
|
| 2230 |
Cerebellar hypoplasia
Short Name
Cerebellar hypoplasia
|
0 |
Tissue |
Jun 6, 2024 |
Jun 6, 2024 |
532: Retinoic acid receptor agonism during cerebellar development leading to impaired locomotor function
|
| 2229 |
Cerebellar neuronal differentiation. Decreased
Short Name
Decreased cerebellar neuronal differentiation
|
0 |
Organ |
Jun 6, 2024 |
Jun 6, 2024 |
532: Retinoic acid receptor agonism during cerebellar development leading to impaired locomotor function
|
| 2228 |
Cerebellar gene expression. Altered
Short Name
Altered cerebellar gene expression
|
0 |
Molecular |
Jun 6, 2024 |
Jun 6, 2024 |
532: Retinoic acid receptor agonism during cerebellar development leading to impaired locomotor function
|
| 2227 |
Disrupted PPAR isoform nuclear signaling
Short Name
Disrupted PPAR isoform nuclear signaling
|
1 |
Molecular |
May 14, 2024 |
May 22, 2024 |
529: Xenobiotic binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism leading to liver steatosis
|
| 2226 |
Stressor binding PPAR isoforms
Short Name
Binding PPAR isoforms
|
1 |
Molecular |
May 8, 2024 |
May 22, 2024 |
529: Xenobiotic binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism leading to liver steatosis
|
| 2225 |
Disrupted Lipid Storage
Short Name
Disrupted Lipid Storage
|
1 |
Cellular |
May 8, 2024 |
May 23, 2024 |
529: Xenobiotic binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism leading to liver steatosis
|
| 2224 |
Dysregulation of transcriptional expression within PPAR signaling network
Short Name
Dysregulation of transcriptional expression within PPAR signaling network
|
1 |
Molecular |
May 8, 2024 |
May 23, 2024 |
529: Xenobiotic binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism leading to liver steatosis
|
| 2223 |
Reduced number of oligodendrocytes
Short Name
Reduced number of oligodendrocytes
|
0 |
Cellular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2222 |
Altered peroxisome proliferator–activated receptor alpha activity
Short Name
PPAR alpha activity, altered
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2221 |
Altered Liver X receptor activity
Short Name
LXR activity, altered
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2220 |
Antagonism, Glucocorticoid hormone receptor
Short Name
GR antagonism
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2219 |
Binding of (ant)agonist to peroxisome proliferator–activated receptor alpha
Short Name
Binding of (ant)agonist to PPAR alpha
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2218 |
Binding of (ant)agonist to liver X receptor
Short Name
Binding of (ant)agonist to liver X receptor
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2217 |
Binding of antagonist to glucocorticoid hormone receptor
Short Name
Binding of antagonist to glucocorticoid hormone receptor
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|