Prototypical Stressors

Showing 326 to 350 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

814	Neostigmine		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
400	Nefazodone, Amiodarone, Metformin, Diclofenac		None
394	Nefazodone, Amiodarone, Flutamide, Benzbromarone, Metformin, Tolcapone, Entacapone, Diclofenac		None
398	Nefazodone, Amiodarone, Benzbromarone, Metformin, Entacapone		None
421	Nefazodone	Nefazodone, CAS-RN: 83366-66-9, DTXSID2023357	None
41	Naproxen	Naproxen, CAS-RN: 22204-53-1, DTXSID4040686	None
230	naphtharazine		None
860	Naphthalene	Naphthalene, CAS-RN: 91-20-3, DTXSID8020913	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
717	Nanoparticles and Micrometer Particles		None
733	Nanoparticles and micrometer		None
224	nanoparticles		3 AOPs 144: Endocytic lysosomal uptake leading to liver fibrosis 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
634	nanomaterials		2 AOPs 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
206	Nafenopin	Nafenopin, CAS-RN: 3771-19-5, DTXSID8020911	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
315	Nabam-sodium	Nabam-sodium, CAS-RN: 142-59-6, DTXSID5020603	242: Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity
588	Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide Pimozide		None
589	Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide		None
268	n/a		None
833	N-Methyl-D-aspartic acid	N-Methyl-D-aspartic acid, CAS-RN: 6384-92-5, DTXSID8041082	475: Binding of chemicals to ionotropic glutamate receptors leads to impairment of learning and memory via loss of drebrin from dendritic spines of neurons
80	N-methyl Carbamates		405: Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function
572	N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide		348: Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory
669	Mycotoxin	Mycotoxin, CAS-RN: NOCAS, DTXSID0040884	None
847	Muristerone A		342: Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade
306	Multi-walled carbon nanotubes		409: Frustrated phagocytosis leads to malignant mesothelioma
403	MS-275	MS-275, CAS-RN: 209783-80-2, DTXSID0041068	274: Histone deacetylase inhibition leads to impeded craniofacial development
222	MPP+		3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits