Prototypical Stressors

Showing 101 to 125 of 855 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

164	Tebufenozide	Tebufenozide, CAS-RN: 112410-23-8, DTXSID4034948	2 AOPs 4: Ecdysone receptor agonism leading to mortality via suppression of Ftz-f1 342: Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade
286	Tebuconazole	Tebuconazole, CAS-RN: 107534-96-3, DTXSID9032113	None
251	TCPOBOP		107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
736	Tamoxifen epoxide	Tamoxifen epoxide, CAS-RN: 92137-93-4, DTXSID40238885	None
172	Tamoxifen	Tamoxifen, CAS-RN: 10540-29-1, DTXSID1034187	3 AOPs 165: Antiestrogen activity leading to ovarian adenomas and granular cell tumors in the mouse 440: Hypothalamus estrogen receptors activity suppression leading to ovarian cancer via ovarian epithelial cell hyperplasia 503: Activation of uterine estrogen receptor-alfa leading to endometrial adenocarcinoma, via epigenetic modulation
616	TAK-242		277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
293	Tacrorimus		None
163	Tacrolimus (also FK506)	Tacrolimus, CAS-RN: 104987-11-3, DTXSID5046354	2 AOPs 154: Inhibition of Calcineurin Activity Leading to Impaired T-Cell Dependent Antibody Response 622: Calcineurin inhibitor induced nephrotoxicity leading to kidney failure
818	Tabun		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
114	T-butyl bicyclophosphorothionate		None
498	Sunlight (wavelength: 290-700 nm)		None
169	Sunitinib malate Sunitinib (INN)		43: Disruption of VEGFR Signaling Leading to Developmental Defects
431	Sulindac	Sulindac, CAS-RN: 38194-50-2, DTXSID4023624	None
658	Sulfur dioxide	Sulfur dioxide, CAS-RN: 7446-09-5, DTXSID6029672	None
434	Sulforaphane	Sulforaphane, CAS-RN: 4478-93-7, DTXSID8036732	None
79	Sulfamethazine	Sulfamethazine, CAS-RN: 57-68-1, DTXSID6021290	None
402	Suberoylanilide hydroxamic acid	Suberoylanilide hydroxamic acid, CAS-RN: 149647-78-9, DTXSID6041133	274: Histone deacetylase inhibition leads to impeded craniofacial development
653	su5402	su5402, CAS-RN: 215543-92-3, DTXSID90415361	None
362	Styrene	Styrene, CAS-RN: 100-42-5, DTXSID2021284	None
663	Stressor:645 Cigarette smoke		None
633	Stressor:624 SARS-CoV-2		379: Binding to ACE2 leading to thrombosis and disseminated intravascular coagulation
497	Stressor:492 Dexamethasone		None
496	Stressor:491 soluble IL-1R (Rilonacept)		None
495	Stressor:488 cinnamic aldehyde		None
584	Stressor:48 Propylthiouracil		None